Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | USP10 | Q14694 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521800 | 0.83 | ATM (0.50) | TDP1ATMMAPTALDH1A1USP10 | |
| SCHEMBL8051408 | 0.81 | TSHR (0.53) | TDP1MAPTALDH1A1L3MBTL1HCAR3 | |
| SCHEMBL31152812 | 0.80 | ATM (0.44) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL31152809 | 0.80 | ATM (0.44) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL2610943 | 0.80 | ATM (0.44) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL10477065 | 0.80 | ATM (0.58) | TDP1ATMMAPTALDH1A1HCAR3 | |
| SCHEMBL26919903 | 0.77 | ATM (0.41) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL31083656 | 0.76 | KMT2A (0.46) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL10687975 | 0.75 | ATM (0.53) | TDP1ATMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL6512614 | 0.75 | TDP1 (0.45) | TDP1ATMMAPTALDH1A1USP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5163970-A | NITRO-P-PHENYLENEDIAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS CONTAINING THESE FOR USE ON KERATIN FIBRES | HANS SCHWARZKOPF GMBH (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5067967-A | Nitro dyes for oxidation color dyes | 501 HANS SCHWARZKOPF GMBH (DE) | 1991-11-26 | — | — | US | disclosed |