Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516747 | 0.81 | TSHR (0.45) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL9687422 | 0.81 | TDP1 (0.51) | TSHRALDH1A1L3MBTL1TDP1HCAR3 | |
| SCHEMBL7809604 | 0.80 | TSHR (0.58) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL7800605 | 0.75 | ALDH3A1 (0.55) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL1887530 | 0.75 | TSHR (0.56) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL1254184 | 0.74 | TDP1 (0.72) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2283806 | 0.73 | MAPT (0.63) | TSHRALDH1A1CYP3A4ALOX15L3MBTL1 | |
| SCHEMBL27475420 | 0.73 | TSHR (0.43) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL4795854 | 0.73 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL10936850 | 0.72 | TSHR (0.55) | TSHRALDH1A1CYP3A4HCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160179-A | Method of producing 4-nitro-m-phenylenediamine sulfate | GIANNOTTI JAMES (US) | 2000-12-12 | — | — | US | claimed |
| US-5350424-A | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-09-27 | — | — | US | disclosed |
| US-5334225-A | Imparts color tone of high chroma; excellent in coloring power and fastness | KAO CORPORATION (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0593038-A1 | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0579204-A2 | Dye composition for a keratinous fiber | KAO CORPORATION (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5041608-A | Dte developers | KAO CORPORATION (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0376078-A2 | Dye composition for keratinous fiber | KAO CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0299497-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4104020-A | OXIDIZABLE DEVELOPER-COUPLER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4046503-A | DEVELOPER-COUPLER HAIR DYES BASED ON ALKOXY-TRIAMINO-PYRIMIDINES | HENKEL & CIE GMBH (DT) | 1977-09-06 | — | — | US | disclosed |
| US-4043750-A | OXIDATION | HENKEL & CIE GMBH (DT) | 1977-08-23 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |