Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334452 | 0.87 | CA1 (0.43) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL5674237 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL95482 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL9687560 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL9318057 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL9027341 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL17780857 | 0.81 | TDP1 (0.47) | ALDH1A1L3MBTL1TDP1GPR35KDM4E | |
| SCHEMBL14676050 | 0.80 | CYP1A2 (0.58) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL14844290 | 0.80 | CYP1A2 (0.58) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL10960330 | 0.80 | CA1 (0.45) | ALDH1A1KMT2AMAPK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |