Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492931 | 0.91 | HSD17B10 (0.50) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL29401067 | 0.91 | HSD17B10 (0.50) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL29441324 | 0.91 | HSD17B10 (0.50) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1770132 | 0.91 | HSD17B10 (0.50) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL109108 | 0.91 | HSD17B10 (0.50) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5549572 | 0.90 | HSD17B10 (0.49) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| Water SCHEMBL3223306 | 0.90 | HSD17B10 (0.49) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8507928 | 0.90 | HSD17B10 (0.49) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| Water SCHEMBL4580188 | 0.90 | HSD17B10 (0.49) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL25933610 | 0.87 | CES2 (0.51) | TDP1SRD5A2CYP2C8KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120825-A | Heat resistant hybrid | HOECHST CELANESE CORP. (US) | 1992-06-09 | — | — | US | disclosed |