Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911477 | 0.86 | CFTR (0.60) | CFTRMEN1KMT2AARVCP | |
| SCHEMBL30118262 | 0.86 | CFTR (0.60) | CFTRMEN1KMT2AARVCP | |
| SCHEMBL18724400 | 0.83 | ABL1 (0.69) | CFTRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24590355 | 0.82 | NPC1 (0.64) | MEN1KMT2AARVCPKDM1A | |
| SCHEMBL12881839 | 0.81 | MAPT (0.62) | MEN1KMT2AARKDM4EALDH1A1 | |
| SCHEMBL2405752 | 0.81 | RECQL (0.60) | CFTRMEN1KMT2AARKDM1A | |
| SCHEMBL3609002 | 0.80 | CFTR (0.60) | CFTRMEN1KMT2AARVCP | |
| SCHEMBL8356874 | 0.80 | MEN1 (0.71) | MEN1KMT2AKDM1A | |
| SCHEMBL2025083 | 0.80 | AR (0.57) | MEN1KMT2AARKDM1AALDH1A1 | |
| SCHEMBL23553882 | 0.79 | VCP (0.71) | CFTRMEN1KMT2AVCPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153511-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2017-04-12 | — | — | EP | disclosed |
| EP-0473980-A1 | Process for the production of 3-alkoxy-2-heteroazolylamino-acrylic acid esters | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |