Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183363 | 0.81 | MAPT (0.50) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL1485755 | 0.81 | HTT (0.72) | HTTMAPTNR4A2ELANETLR8 | |
| Hydrochloric Acid SCHEMBL28039133 | 0.79 | HTT (0.69) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL29118509 | 0.79 | HTT (0.47) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL14618512 | 0.78 | HTT (0.67) | HTTMAPTNR4A2ELANETLR8 | |
| SCHEMBL19848067 | 0.77 | HTT (0.46) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL28875347 | 0.76 | MAPT (0.48) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL309485 | 0.76 | TLR8 (0.53) | HTTMAPTNR4A2TLR8CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL11314241 | 0.76 | MAPT (0.44) | HTTMAPTNR4A2ELANEKAT2B | |
| SCHEMBL14226176 | 0.76 | MAPT (0.44) | HTTMAPTNR4A2ELANEKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | claimed |