SCHEMBL309485

SCHEMBL309485

CCCCNc1ccccc1NCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.53
HTT P42858 2/20 0.50
MAPT P10636 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
UTS2R Q9UKP6 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
APAF1 O14727 1/20 0.47
ALDH1A1 P00352 1/20 0.47
BCHE P06276 2/20 0.46
POLB P06746 1/20 0.46
TRPC3 Q13507 1/20 0.46
TRPC4 Q9UBN4 1/20 0.46
TRPC5 Q9UL62 1/20 0.46
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1724131 0.93 L3MBTL1 (0.51) TLR8HTTMAPTCYP1A2CYP3A4
SCHEMBL28739378 0.91 TLR8 (0.47) TLR8HTTMAPTCYP1A2CYP3A4
SCHEMBL11266466 0.91 L3MBTL1 (0.54) TLR8HTTMAPTL3MBTL1NPSR1
SCHEMBL8535750 0.91 L3MBTL1 (0.54) TLR8HTTMAPTL3MBTL1NPSR1
SCHEMBL30174089 0.91 L3MBTL1 (0.54) TLR8HTTMAPTL3MBTL1NPSR1
SCHEMBL11266453 0.91 L3MBTL1 (0.54) TLR8HTTMAPTL3MBTL1NPSR1
SCHEMBL14618512 0.88 HTT (0.67) TLR8HTTMAPTCYP1A2CYP3A4
SCHEMBL1485755 0.87 HTT (0.72) TLR8HTTMAPTCYP1A2CYP3A4
SCHEMBL29734978 0.86 KCNH3 (0.54) TLR8HTTMAPTCYP1A2CYP3A4
SCHEMBL6687184 0.86 KCNH3 (0.54) TLR8HTTMAPTCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7329708-B2 Functionalized poly(arylene ether) composition and method GENERAL ELECTRIC COMPANY (US) 2008-02-12 US claimed
US-7148296-B2 Capped poly(arylene ether) composition and process GENERAL ELECTRIC COMPANY (US) 2006-12-12 US claimed
US-7119136-B2 Flame-retardant thermoset composition, method, and article GENERAL ELECTRIC COMPANY (US) 2006-10-10 US claimed
US-7101923-B2 Flame-retardant thermoset composition, method, and article GENERAL ELECTRIC COMPANY (US) 2006-09-05 US claimed
US-20060167142-A9 FLAME-RETARDANT THERMOSET COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY 2006-07-27 US claimed
US-7067595-B2 Poly (arylene ether) composition and method GENERAL ELECTRIC COMPANY (US) 2006-06-27 US claimed
WO-2006023371-A1 FUNCTIONALIZED POLY(ARYLENE ETHER) COMPOSITION AND METHOD GENERAL ELECTRIC COMPANY (US) 2006-03-02 WO claimed
US-20060041086-A1 Functionalized poly(arylene ether) composition and method SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-02-23 US claimed
US-20050075426-A1 Flame-retardant thermoset composition, method, and article CITIBANK, N.A., AS COLLATERAL AGENT 2005-04-07 US claimed
US-20050075463-A1 Poly (arylene ether) composition and method CITIBANK, N.A., AS COLLATERAL AGENT 2005-04-07 US claimed
US-20050075462-A1 Capped poly(arylene ether) composition and process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2005-04-07 US claimed
US-20050075427-A1 Flame-retardant thermoset composition, method, and article GENERAL ELECTRIC COMPANY 2005-04-07 US claimed
EP-4640796-A1 LUBRICATING COMPOSITION FOR GEAR FLUIDS AND WET BRAKES Afton Chemical Corporation (US) 2025-10-29 EP disclosed
CN-117285973-B Phosphorus antiwear system for improved gear protection 雅富顿化学公司 2024-09-10 CN disclosed
EP-4296338-B1 PHOSPHORUS ANTIWEAR SYSTEM FOR IMPROVED GEAR PROTECTION AFTON CHEMICAL CORP (US) 2024-05-15 EP disclosed
CN-117487047-A Phosphonic acid functionalized polymer, multifunctional styrene polymer and application thereof 国家电投集团氢能科技发展有限公司 2024-02-02 CN disclosed
EP-0291950-A1 Process and composition for stabilization of ar-brominated styrenic monomer against premature polymerization GE CHEMICALS, INC. (US) 1988-11-23 EP disclosed
US-4337103-A FUNCTIONALLY TERMINATED RUBBER HERCULES INCORPORATED (US) 1982-06-29 US disclosed
US-3996024-A A LIQUID HYDROCARBON FUEL WITH THE SALT OF A HYDROCARBYL-SUBSTITUTED AMINE AND A CARBOXYLIC ACID CHEVRON RESEARCH COMPANY (US) 1976-12-07 US disclosed
US-3982975-A UNCURED CARBOXYLATED RUBBER, EPOXIDE CURING AGENT, PHENYLENEDIAMINE ANTIOXIDANT HERCULES INCORPORATED (US) 1976-09-28 US disclosed