SCHEMBL9687889

SCHEMBL9687889

N=C=O.N=C=O.N=C=O.[SiH3]Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
CA4 P22748 1/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
SRC P12931 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNA3 P22001 1/20 0.33
ALOX15 P16050 1/20 0.33
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
GAPDH P04406 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222149 0.84
Water SCHEMBL27842141 0.81
SCHEMBL9005960 0.81
Hydrochloric Acid SCHEMBL7626638 0.81 LTA4H (0.50) LTA4HTSHRCA4CA1CA2
SCHEMBL9005962 0.81
Diphenylether SCHEMBL1322389 0.79 LTA4H (0.67) LTA4HTSHRCA1CA2CA9
Diphenylether SCHEMBL3447175 0.79 LTA4H (0.67) LTA4HTSHRCA1CA2CA9
Diphenylether SCHEMBL42900 0.79 LTA4H (0.67) LTA4HTSHRCA1CA2CA9
Diphenylether SCHEMBL28231494 0.79 LTA4H (0.67) LTA4HTSHRCA1CA2CA9
Anisole SCHEMBL15125 0.75 CA4 (0.70) LTA4HCA4CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153068-A Discoloration inhibition SEKISUI FINE CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed
US-4766037-A Photodegradable microcapsules FUJI PHOTO FILM CO., LTD. (JP) 1988-08-23 US disclosed
US-4433127-A SILYL ISOCYANATE, ORGANO-TITANIUM-OXYGEN-PHOSPHORUS COMPOUND MATSUMOTO SEIYAKU KOGYO KABUSHIKI KAISHA (JP) 1984-02-21 US disclosed
US-4176131-A Chemical process BRISTOL-MYERS COMPANY (US) 1979-11-27 US disclosed