Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894932 | 0.88 | CASP1 (0.42) | CASP1MAPTTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10893099 | 0.86 | CASP1 (0.41) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL29377795 | 0.83 | CASP1 (0.42) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL126188 | 0.83 | CASP1 (0.42) | CASP1MAPTTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5240582 | 0.81 | CASP1 (0.41) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL14674256 | 0.81 | CASP1 (0.34) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL7568808 | 0.81 | MAPT (0.49) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL2671870 | 0.81 | CASP1 (0.34) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL9025493 | 0.81 | MAPT (0.49) | CASP1MAPTTDP1MEN1KMT2A | |
| SCHEMBL10635917 | 0.81 | MAPT (0.49) | CASP1MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |