SCHEMBL9687962

SCHEMBL9687962

Cc1ccccc1-c1c(C)c(C)c(C)c(N)c1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.41
HEXB P07686 1/20 0.41
CYP3A4 P08684 2/20 0.39
NPC1 O15118 2/20 0.39
CASP3 P42574 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
SENP7 Q9BQF6 2/20 0.39
SENP6 Q9GZR1 2/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
HBB P68871 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.37
CD44 P16070 1/20 0.37
SENP8 Q96LD8 1/20 0.36
MYC P01106 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386112 1.00 HEXA (0.41) HEXAHEXBCYP3A4NPC1CASP3
Hydrochloric Acid SCHEMBL8740059 0.98 CYP3A4 (0.41) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL29512916 0.87 HEXA (0.43) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL366602 0.87 HEXA (0.43) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL8609589 0.85 HEXA (0.42) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL28844141 0.82 TSHR (0.47) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL25316689 0.80 ALDH1A1 (0.38) CYP3A4NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL31603849 0.80 ALDH1A1 (0.38) CYP3A4NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL31054315 0.80 HEXA (0.47) HEXAHEXBCYP3A4NPC1CASP3
SCHEMBL28558745 0.79 ALDH1A1 (0.40) HEXAHEXBCYP3A4NPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098972-A Terpolymerization of vinyl monomers ATOCHEM (FR) 1992-03-24 US disclosed
US-5082911-A Ally ethers ATOCHEM (FR) 1992-01-21 US disclosed