Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SHBG | P04278 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100534 | 0.88 | CYP17A1 (0.78) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL9687638 | 0.86 | HIF1A (0.52) | CYP17A1SMN1; SMN2LMNASHBGHSD17B10 | |
| SCHEMBL9687624 | 0.86 | HIF1A (0.52) | CYP17A1SMN1; SMN2LMNASHBGHSD17B10 | |
| SCHEMBL28100316 | 0.86 | CYP17A1 (0.78) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL9688279 | 0.83 | CYP19A1 (0.53) | CYP17A1LMNACYP19A1MAPTCYP3A4 | |
| SCHEMBL4661581 | 0.82 | CYP17A1 (1.00) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL12403281 | 0.82 | CYP17A1 (1.00) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL10706045 | 0.81 | CYP17A1 (0.78) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL9653514 | 0.81 | CYP17A1 (0.78) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG | |
| SCHEMBL10706443 | 0.81 | CYP17A1 (0.76) | CYP17A1SMN1; SMN2LMNAALDH1A1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082835-A | Antiinflammatory agents | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-01-21 | — | — | US | disclosed |
| US-5053404-A | Antiinflammatory and antiasthmatic agents | RICHTER GEDEON VEGYESZETI GYAR R. T. (HU) | 1991-10-01 | — | — | US | disclosed |
| EP-0387091-A2 | Steroid diols, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-12 | — | — | EP | disclosed |