Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | SHBG | P04278 | 3/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687624 | 1.00 | HIF1A (0.52) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9688326 | 0.86 | CYP17A1 (0.69) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9687413 | 0.83 | NR3C1 (0.50) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9687420 | 0.83 | NR3C1 (0.50) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9655906 | 0.83 | HIF1A (0.62) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9655893 | 0.83 | HIF1A (0.62) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL9657103 | 0.83 | HIF1A (0.62) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL10599706 | 0.79 | HIF1A (0.64) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL1180510 | 0.79 | NR3C2 (0.71) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 | |
| SCHEMBL10599694 | 0.79 | HIF1A (0.64) | HIF1ANR3C2SMN1; SMN2LMNASERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082835-A | Antiinflammatory agents | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-01-21 | — | — | US | disclosed |
| US-5053404-A | Antiinflammatory and antiasthmatic agents | RICHTER GEDEON VEGYESZETI GYAR R. T. (HU) | 1991-10-01 | — | — | US | disclosed |
| EP-0387090-A2 | Steroid derivatives,processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-12 | — | — | EP | disclosed |
| EP-0387091-A2 | Steroid diols, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-12 | — | — | EP | disclosed |