Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303437 | 0.83 | KDM4E (0.36) | TDP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8042700 | 0.78 | MAPT (0.45) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL7520417 | 0.76 | TDP1 (0.46) | TDP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL15524283 | 0.74 | SELL (0.57) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL14691383 | 0.73 | TDP1 (0.53) | TDP1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL4734822 | 0.73 | KDM4E (0.50) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL332091 | 0.73 | GLRA3 (0.46) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL9080891 | 0.71 | GLRA3 (0.44) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL1406034 | 0.71 | GLRA3 (0.44) | TDP1MAPTSELLSELPKDM4E | |
| SCHEMBL22722987 | 0.71 | GLRA3 (0.44) | TDP1MAPTSELLSELPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |