Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688386 | 1.00 | PPARG (0.65) | PPARGNFE2L2LMNAKDM4EMEN1 | |
| SCHEMBL14492055 | 0.79 | PPARG (1.00) | PPARGNFE2L2LMNA | |
| SCHEMBL27591358 | 0.77 | PPARG (1.00) | PPARGNFE2L2LMNA | |
| SCHEMBL14492053 | 0.77 | PPARG (1.00) | PPARGNFE2L2LMNA | |
| SCHEMBL14492067 | 0.77 | PPARG (1.00) | PPARGNFE2L2LMNA | |
| SCHEMBL28192166 | 0.75 | PPARG (0.96) | PPARGNFE2L2LMNA | |
| SCHEMBL28240283 | 0.75 | PPARG (0.96) | PPARGNFE2L2LMNA | |
| SCHEMBL7336404 | 0.75 | TDP1 (0.60) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14492057 | 0.73 | PPARG (1.00) | PPARGNFE2L2LMNASMN1; SMN2 | |
| SCHEMBL14492063 | 0.71 | PPARG (0.86) | PPARGNFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |