Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922623 | 0.94 | GRM5 (0.60) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8921825 | 0.90 | HDAC1 (0.58) | GRM5HDAC1CYP2C9CYP2C19GRIN2B | |
| SCHEMBL11474488 | 0.79 | SMN1; SMN2 (0.60) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL3821618 | 0.78 | MAPT (0.56) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL4563772 | 0.76 | CYP1A2 (0.69) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8713970 | 0.75 | ALDH1A1 (0.49) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL12190517 | 0.74 | GRM5 (0.58) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL3336130 | 0.74 | CYP1A2 (0.59) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL29741462 | 0.74 | CYP1A2 (0.59) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL781659 | 0.73 | CYP1A2 (0.87) | GRM5ALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |