Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688698 | 0.83 | RECQL (0.66) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9688156 | 0.82 | MAPT (0.46) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9688779 | 0.82 | RECQL (0.46) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9689326 | 0.82 | NPC1 (0.54) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL8807589 | 0.81 | RECQL (0.67) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9688754 | 0.80 | RECQL (0.43) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9689070 | 0.80 | SMN1; SMN2 (0.48) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL30543430 | 0.80 | RECQL (0.65) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9526005 | 0.79 | RECQL (0.70) | RECQLLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL9329215 | 0.79 | RECQL (1.00) | RECQLLMNAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039298-A | Preparation method of (strych) -5-benzoyl-2, 3-dihydro-1H-pyridine-1-carboxylic acid | 北京云鹏鹏程医药科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-119039298-A | Preparation method of (strych) -5-benzoyl-2, 3-dihydro-1H-pyridine-1-carboxylic acid | 北京云鹏鹏程医药科技有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-119039298-A | Preparation method of (strych) -5-benzoyl-2, 3-dihydro-1H-pyridine-1-carboxylic acid | 北京云鹏鹏程医药科技有限公司 | 2024-11-29 | — | — | CN | disclosed |
| EP-0486807-A1 | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1992-05-27 | — | — | EP | disclosed |
| US-5082951-A | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates (I) and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |