Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329215 | 0.82 | RECQL (1.00) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL10515603 | 0.81 | PBRM1 (0.50) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL29229 | 0.81 | LMNA (0.44) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL9688698 | 0.79 | RECQL (0.66) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL9688818 | 0.79 | RECQL (0.66) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL27256801 | 0.79 | RECQL (0.69) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL10939276 | 0.78 | ALDH1A1 (0.47) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL10365910 | 0.78 | RECQL (0.64) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL27995751 | 0.78 | RECQL (0.59) | RECQLMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL3504148 | 0.77 | LMNA (0.41) | RECQLMAPTLMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231996-B1 | NOVEL AMINO ACID DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-10-06 | — | — | EP | disclosed |
| US-4931450-A | Amino acid derivatives | NOVO INDUSTRI A/S (DK) | 1990-06-05 | — | — | US | disclosed |
| EP-0231996-A2 | Novel amino acid derivatives | NOVO NORDISK A/S (DK) | 1987-08-12 | — | — | EP | disclosed |