Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852227 | 0.81 | NPC1 (0.66) | LMNAMAPTTP53RXFP1NPC1 | |
| SCHEMBL25083904 | 0.80 | MAPT (0.56) | LMNAMAPTTP53RXFP1NPC1 | |
| SCHEMBL28952954 | 0.76 | SMN1; SMN2 (0.75) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL4078154 | 0.76 | TP53 (0.48) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL32679828 | 0.73 | CYP19A1 (0.66) | LMNAMAPTTP53THRBRAB9A | |
| SCHEMBL3979477 | 0.72 | LMNA (0.43) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL8804007 | 0.72 | LMNA (0.43) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL9567848 | 0.71 | PTGS1 (0.49) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL25883843 | 0.71 | CYP19A1 (0.61) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL8999461 | 0.70 | PLCG1 (0.51) | LMNAMAPTTP53THRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473980-A1 | Process for the production of 3-alkoxy-2-heteroazolylamino-acrylic acid esters | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |