Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110227 | 0.82 | GAA (0.58) | FFAR1DRD2DRD4DRD3NPC1 | |
| SCHEMBL6429357 | 0.80 | FFAR1 (0.52) | FFAR1PLA2G4BS1PR1S1PR3S1PR5 | |
| SCHEMBL4981505 | 0.79 | KCNA3 (0.73) | FFAR1PLA2G4BDRD2DRD4DRD3 | |
| SCHEMBL5543364 | 0.78 | FFAR1 (0.61) | FFAR1PLA2G4BDRD2DRD4DRD3 | |
| SCHEMBL20325128 | 0.78 | KCNH2 (0.56) | FFAR1POLBGAASMN1; SMN2 | |
| SCHEMBL257764 | 0.78 | DRD2 (0.64) | FFAR1PLA2G4BDRD2DRD4DRD3 | |
| SCHEMBL3652537 | 0.78 | NR5A1 (0.55) | PLA2G4BNPC1RAB9A | |
| SCHEMBL4982709 | 0.77 | KCNA3 (0.70) | FFAR1PLA2G4BDRD2DRD4DRD3 | |
| SCHEMBL13979617 | 0.77 | DRD2 (0.62) | FFAR1PLA2G4BDRD2DRD4DRD3 | |
| SCHEMBL13072255 | 0.77 | FFAR1 (0.64) | FFAR1S1PR1NPC1RAB9AS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |