Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632305 | 0.80 | GPBAR1 (0.64) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| SCHEMBL9689103 | 0.79 | MAPT (0.41) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9689743 | 0.77 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| SCHEMBL9688226 | 0.77 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| SCHEMBL9689503 | 0.76 | NPC1 (0.56) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9688773 | 0.76 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A | |
| SCHEMBL17148057 | 0.76 | GPBAR1 (0.46) | CYSLTR1ALOX5GPBAR1TP53LMNA | |
| Hydrochloric Acid SCHEMBL9688620 | 0.75 | RAB9A (0.60) | MAPK1MEN1KMT2ATP53LMNA | |
| Hydrochloric Acid SCHEMBL9688706 | 0.75 | RAB9A (0.64) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9689538 | 0.75 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |