Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769978 | 0.83 | TSHR (0.42) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL1576398 | 0.82 | PTGDR2 (0.51) | ALDH1A1MEN1KMT2APTGDR2HTR2A | |
| SCHEMBL10284105 | 0.80 | HTR2C (0.41) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL20037330 | 0.80 | KMT2A (0.46) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL27645781 | 0.78 | KDM4E (0.41) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL9691149 | 0.77 | PGR (0.46) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL4054875 | 0.74 | KDM4E (0.53) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL9689228 | 0.72 | PLK1 (0.44) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL2591249 | 0.71 | KDM4E (0.49) | ALDH1A1HSD17B10KDM4EHPGDPTGDR2 | |
| Hydrochloric Acid SCHEMBL9691581 | 0.71 | PLK1 (0.43) | ALDH1A1HSD17B10KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171037-B1 | 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | disclosed |