Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689601 | 0.88 | NPC1 (0.41) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL9689503 | 0.88 | NPC1 (0.56) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL9689344 | 0.81 | SMN1; SMN2 (0.44) | LOXL2NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL21104650 | 0.77 | EPHX2 (0.46) | LOXL2ALOX5EPHX2HDAC6 | |
| SCHEMBL9687773 | 0.74 | CYSLTR2 (0.41) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL9689626 | 0.72 | NPC1 (0.59) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL15689588 | 0.72 | PTGER4 (0.51) | LOXL2NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL21104408 | 0.71 | PTGER4 (0.52) | ALOX5EPHX2HDAC6 | |
| SCHEMBL9689609 | 0.70 | NPC1 (0.48) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL15713316 | 0.70 | PTGER4 (0.54) | ALOX5EPHX2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |