Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9689602 | 0.86 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9688459 | 0.82 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9688324 | 0.81 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| Hydrochloric Acid SCHEMBL9688784 | 0.80 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9688760 | 0.80 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9688225 | 0.79 | GPBAR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9689357 | 0.78 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9460703 | 0.74 | ALOX5 (0.61) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL10465701 | 0.73 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Hydrochloric Acid SCHEMBL9688827 | 0.72 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |