Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9689669 | 0.82 | CYP19A1 (0.53) | CYP19A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10570210 | 0.80 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9688442 | 0.79 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9688871 | 0.79 | CYP19A1 (0.38) | CYP19A1MAOBBRD4ACHE | |
| Hydrochloric Acid SCHEMBL9688723 | 0.79 | CYP19A1 (0.44) | CYP19A1LMNACYP3A4HSP90AA1 | |
| Hydrochloric Acid SCHEMBL9687944 | 0.79 | MAPT (0.49) | CYP19A1LMNAACHE | |
| Hydrochloric Acid SCHEMBL9688795 | 0.79 | CYP19A1 (0.46) | CYP19A1KDM4E | |
| SCHEMBL14699201 | 0.74 | KLKB1 (0.54) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9688353 | 0.73 | CYP19A1 (0.52) | CYP19A1LMNACA12CA1CA2 | |
| SCHEMBL30474877 | 0.69 | ACHE (0.56) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298921-B1 | 1,2-BENZISOXAZOLES AND 1,2-BENZISOTHIAZOLES | CIBA-GEIGY AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| US-4957931-A | ANTICONVULSANTS, TREATMENT OF EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| US-4859691-A | Certain 1,2-benzisoxazole derivatives | CIBA-GEIGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0298921-A1 | 1,2-Benzisoxazoles and 1,2-benzisothiazoles | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |