Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599494 | 0.77 | TSHR (0.46) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL4084303 | 0.77 | PLK1 (0.54) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL826816 | 0.77 | TSHR (0.46) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL3792160 | 0.77 | PLK1 (0.58) | HPGDMEN1KMT2AKDM4E | |
| SCHEMBL31060081 | 0.77 | PLK1 (0.58) | HPGDMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4085351 | 0.76 | PLK1 (0.53) | POLBHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL8791785 | 0.75 | KDM4E (0.44) | MEN1KMT2AMAPK1GLAPKM | |
| SCHEMBL10635530 | 0.74 | KMT2A (0.56) | MEN1KMT2AMAPK1KDM4EGAA | |
| SCHEMBL8791132 | 0.74 | KDM4E (0.43) | MEN1KMT2AMAPK1KDM4EGAA | |
| SCHEMBL827674 | 0.72 | CNR2 (0.44) | POLBHPGDPKMKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |