SCHEMBL9690433

SCHEMBL9690433

N=C(N)NC(CS)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
ALOX15 P16050 1/20 0.57
NFKB1 P19838 1/20 0.57
PTGS2 P35354 1/20 0.57
THPO P40225 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ACE P12821 1/20 0.52
FOLH1 Q04609 1/20 0.48
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
TGFBR1 P36897 1/20 0.41
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
PTGS1 P23219 2/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
CPN1 P15169 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2793250 1.00 KDM4E (0.57) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL13299210 0.84 KDM4E (0.39) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL12807815 0.84 KDM4E (0.39) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL478268 0.82 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1289325 0.82 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL478269 0.82 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL12205433 0.81 KDM4E (0.47) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL29543010 0.80 TGFBR1 (0.42) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL2931883 0.79 ACE (0.45) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL345247 0.78 TGFBR1 (0.41) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN claimed
US-20170157170-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF KENVUE BRANDS LLC 2017-06-08 US claimed
EP-3175888-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF Johnson & Johnson Consumer Inc. (US) 2017-06-07 EP claimed
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 CN disclosed
US-20190151355-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF JOHNSON & JOHNSON CONSUMER INC (US) 2019-05-23 US disclosed
US-10238685-B2 Compositions containing polymeric sulfur and uses thereof JOHNSON & JOHNSON CONSUMER INC. (US) 2019-03-26 US disclosed
US-20170157170-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF KENVUE BRANDS LLC 2017-06-08 US disclosed
EP-3175888-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF Johnson & Johnson Consumer Inc. (US) 2017-06-07 EP disclosed
CN-1901924-B Method for inhibiting bacterial colonisation WOMENS & CHILDRENS HOSPITAL 2010-04-28 CN disclosed
US-5089381-A SILVER HALIDE RECORDING MATERIAL AGFA-GEVAERT AG (DE) 1992-02-18 US disclosed