Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.83 |
| ▸ | NPC1 | O15118 | 3/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | CYP2E1 | P05181 | 10/20 | 0.63 |
| ▸ | CYP2C8 | P10632 | 10/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.63 |
| ▸ | CYP2B6 | P20813 | 10/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.63 |
| ▸ | BRS3 | P32247 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NOS2 | P35228 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692851 | 0.90 | NPC1 (0.67) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9690543 | 0.89 | CYP2E1 (0.67) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9693004 | 0.89 | RAB9A (0.66) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9339322 | 0.88 | RAB9A (0.66) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9692749 | 0.87 | CYP2D6 (0.65) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9693023 | 0.85 | RAB9A (0.70) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL15693621 | 0.85 | NPC1 (0.81) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9692982 | 0.85 | RAB9A (0.62) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL9693079 | 0.84 | RAB9A (0.60) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL25317747 | 0.82 | RAB9A (0.82) | RAB9ANPC1PKMSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081253-A | IMIDAZO(4,5-C)PYRIDINES AS ANTIOSTEOPOROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | claimed |
| EP-0434405-A1 | Imidazo[4,5-c]pyridines as antiosteoporotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-26 | — | — | EP | claimed |
| US-5081253-A | IMIDAZO(4,5-C)PYRIDINES AS ANTIOSTEOPOROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0434405-A1 | Imidazo[4,5-c]pyridines as antiosteoporotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |
| US-5001238-A | Production of certain 2-phenylalkylthio-and 2-phenylalkylsulfinyl imidazo[4,]pyridines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |