Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689321 | 0.88 | CNR1 (0.69) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9691472 | 0.88 | CNR1 (0.68) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL9690665 | 0.79 | CNR2 (0.73) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL10459889 | 0.78 | CNR2 (0.55) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL9769990 | 0.78 | ALDH1A1 (0.65) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL9691562 | 0.78 | CNR1 (0.69) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL9691672 | 0.78 | CNR1 (0.54) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| SCHEMBL9689445 | 0.78 | CNR1 (0.54) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9691111 | 0.77 | CNR2 (0.54) | CNR1CNR2ALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9691731 | 0.77 | CNR1 (0.53) | CNR1CNR2ALDH1A1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171037-B1 | 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-06-17 | — | — | EP | claimed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | claimed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | claimed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | claimed |