Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061474 | 1.00 | CA2 (0.44) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9691197 | 1.00 | CA2 (0.44) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9344192 | 0.96 | PLA2G2C (0.43) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9344197 | 0.96 | PLA2G2C (0.43) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9344204 | 0.96 | PLA2G2C (0.43) | CA2CA9CA1CA4CA7 | |
| SCHEMBL5071377 | 0.94 | PLA2G2C (0.45) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9625505 | 0.94 | PLA2G2C (0.45) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9625787 | 0.94 | PLA2G2C (0.45) | CA2CA9CA1CA4CA7 | |
| SCHEMBL9625785 | 0.94 | PLA2G2C (0.45) | CA2CA9CA1CA4CA7 | |
| SCHEMBL13219933 | 0.94 | PLA2G2C (0.45) | CA2CA9CA1CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079825-B1 | COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2010-07-21 | — | — | EP | disclosed |
| EP-0490407-A2 | Process for the enzymatic separation of the optical isomers of tosyloxy-alkanols | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1992-06-17 | — | — | EP | disclosed |