Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691656 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL9835712 | 0.86 | CA1 (0.36) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL9835716 | 0.86 | CA1 (0.36) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL1249258 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10GLO1ALOX15 | |
| SCHEMBL9836706 | 0.74 | ZDHHC7 (0.42) | ALDH1A1CYP2D6CYP2C19CYP2C9FAAH | |
| SCHEMBL9836703 | 0.74 | ZDHHC7 (0.42) | ALDH1A1CYP2D6CYP2C19CYP2C9FAAH | |
| SCHEMBL903306 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL14616293 | 0.71 | CYP2D6 (0.51) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL1759140 | 0.71 | CYP2D6 (0.51) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL7535763 | 0.71 | CYP2D6 (0.51) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |