SCHEMBL9692156

SCHEMBL9692156

COc1c(-c2[c]ccs2)sc(-c2cccs2)c1OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 3/20 0.35
GAA P10253 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
RPS6KB2 Q9UBS0 2/20 0.34
DPP4 P27487 1/20 0.34
NPC1 O15118 6/20 0.33
RAB9A P51151 6/20 0.33
MAPT P10636 3/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692163 0.90 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL9692161 0.84 RPS6KB2 (0.43) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL9691451 0.77 RPS6KB2 (0.41) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL9692168 0.74 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL696954 0.73 KDM4E (0.40) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL7449560 0.69 DPP4 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL4732974 0.69 DPP4 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL10584511 0.65 RPS6KB2 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL18133657 0.64 ERN1 (0.50) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL650323 0.64 MEN1 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098529-A ELECTROCHEMICAL PROCESS FOR THE PRODUCTION OF ELECTRICALLY CONDUCTING POLY(ALKOXYTHIOPHENES) WITH CARBOXYLIC ACIDS ADDED HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-24 US disclosed