Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732974 | 0.86 | DPP4 (0.47) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL7449560 | 0.86 | DPP4 (0.47) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL9692156 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL2779806 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL3545 | 0.71 | L3MBTL1 (0.57) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL16291133 | 0.71 | L3MBTL1 (0.57) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL2782543 | 0.70 | CYP2E1 (0.39) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL177819 | 0.70 | — | — | |
| SCHEMBL17468570 | 0.70 | LTA4H (0.40) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Fluoride SCHEMBL491501 | 0.68 | L3MBTL1 (0.55) | KDM4EALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106938985-A | A kind of 5 amide groups quinolines of alkenyl 8 and its one-pot preparation thereof | 湖南大学 | 2017-07-11 | — | — | CN | claimed |
| EP-2336131-A1 | Hydantoin compounds | Eisai R&D Management Co., Ltd. (JP) | 2011-06-22 | — | — | EP | claimed |
| US-20100113446-A1 | HYDANTOIN COMPOUNDS | GALLAGHER JR BRIAN M | 2010-05-06 | — | — | US | claimed |
| US-7666875-B2 | 1,3,8-triazaspiro(4,5)decane derivatives; antiinflammatory agent for treating rheumatoid arthritis, allergic, multiple sclerosis, autoimmune disease such as inflammatory bowel disease | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-02-23 | — | — | US | claimed |
| CN-101263141-A | Hydantoin compounds | EISAI R&D MAN CO LTD (JP) | 2008-09-10 | — | — | CN | claimed |
| EP-1888583-A2 | HYDANTOIN COMPOUNDS | Eisai Co., Ltd. (JP) | 2008-02-20 | — | — | EP | claimed |
| WO-2006128143-A2 | HYDANTOIN COMPOUNDS | EISAI CO., LTD. (JP) | 2006-11-30 | — | — | WO | claimed |
| US-20060270696-A1 | Hydantoin compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-11-30 | — | — | US | claimed |
| US-5861400-A | TREATING RESISTANCE TO AN ANTHRACYLCINE ANTIBIOTIC WITH ADIKETOPIPERAZINE COMPOUND | XENOVA LIMITED (GB) | 1999-01-19 | — | — | US | claimed |
| EP-0100527-B1 | 4H-1,4-BENZOTHIAZINES FOR USE AS MEDICAMENTS | BAYER AG (DE) | 1987-01-07 | — | — | EP | claimed |
| CN-115010716-B | Polysubstituted pyridine derivative and preparation method thereof | 云南大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-117327029-A | Azole derivative and preparation method thereof | 云南大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-113861181-B | Polysubstituted isothiazole derivative and preparation method thereof | 云南大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114751864-B | Polysubstituted imidazole derivative and preparation method thereof | 云南大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116284027-A | Polysubstituted pentacyclic spiro indoline derivative and preparation method thereof | 云南大学 | 2023-06-23 | — | — | CN | disclosed |
| WO-1990008145-A1 | ANTI-INFLAMMATORY 1-HETEROARYL-3-ACYL-2-OXINDOLES | PFIZER INC. (US) | 1990-07-26 | — | — | WO | disclosed |
| WO-1989005581-A1 | ANTIFUNGAL CARBINOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-29 | — | — | WO | disclosed |
| US-4716160-A | Certain 7-amino-pyrazolo[4,3-b]pyridines useful in treating inflammatory and allergic disorders | BEECHAM GROUP P.L.C. (GB) | 1987-12-29 | — | — | US | disclosed |
| EP-0207593-A1 | Pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |
| US-4099001-A | [[[Imidazolidinyl amino]carbonyl]amino]acetyl cephalosporin derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270696-A1 | Hydantoin compounds | HNMT, HLA-DRB1, SSB | KDM4E 1585/4885ALDH1A1 496/4885HPGD 111/4885 |
| US-20100113446-A1 | HYDANTOIN COMPOUNDS | HNMT, HLA-DRB1, SSB | KDM4E 1585/4885ALDH1A1 496/4885HPGD 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.