Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678403 | 0.99 | KCNH2 (0.49) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9678420 | 0.84 | KCNH2 (0.50) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9678401 | 0.84 | KCNH2 (0.52) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9447426 | 0.83 | KCNH2 (0.51) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9447468 | 0.83 | KCNH2 (0.52) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9676515 | 0.80 | KCNH2 (0.54) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9677412 | 0.79 | KCNH2 (0.55) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL10878888 | 0.78 | KCNH2 (0.54) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9628026 | 0.77 | KCNH2 (0.76) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL9689700 | 0.76 | KCNH2 (0.54) | KCNH2CACNA1FCHRM2ACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082850-A | PIPERIDINE DERIVATIVES AND THERAPEUTIC AND PREVENTIVE AGENTS FOR ARRHYTHMIA CONTAINING SAME | EISAI CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |