Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9757612 | 0.98 | KDM4E (0.39) | KDM4EPOLBMAPTNPSR1ACHE | |
| SCHEMBL17998034 | 0.85 | POLB (0.38) | KDM4EPOLBMAPTNPSR1ACHE | |
| SCHEMBL8036573 | 0.80 | MAPT (0.48) | KDM4EPOLBMAPTNPSR1ACHE | |
| Hydrochloric Acid SCHEMBL10426497 | 0.78 | MAPT (0.46) | KDM4EPOLBMAPTNPSR1ACHE | |
| SCHEMBL9348395 | 0.76 | KDM4E (0.55) | KDM4EPOLBMAPTNPSR1ACHE | |
| SCHEMBL9694188 | 0.75 | TNF (0.38) | KDM4EPOLBMAPTNPSR1GAA | |
| Hydrochloric Acid SCHEMBL9757671 | 0.74 | TNF (0.37) | KDM4EPOLBGAATSHRMAPK1 | |
| SCHEMBL9826944 | 0.72 | IDO1 (0.42) | POLBMAPTNPSR1GAACYP3A4 | |
| SCHEMBL27358216 | 0.72 | KDM4E (0.33) | KDM4EPOLB | |
| SCHEMBL22513203 | 0.72 | KDM4E (0.33) | KDM4EPOLBMAPTNPSR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2950773-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2019-03-13 | — | — | EP | claimed |
| EP-0370880-B1 | TRIALKOXY-SUBSTITUTED M-PHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS COUPLING AGENTS IN THE OXIDATION DYEING OF KERATINIC FIBRES, ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1992-11-11 | — | — | EP | claimed |
| US-5002585-A | HAIR DYES, USED WITH PHENYLENEDIAMINES, AMINOPHENOLS AND AMINOPYRIDINES | L'OREAL (FR) | 1991-03-26 | — | — | US | claimed |
| EP-0370880-A1 | Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair | L'OREAL (FR) | 1990-05-30 | — | — | EP | claimed |
| EP-2950773-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2019-03-13 | — | — | EP | disclosed |
| EP-2950773-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2019-03-13 | — | — | EP | disclosed |
| US-9585824-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 2 in a medium comprising a fatty substance, processes and device | L'OREAL (FR) | 2017-03-07 | — | — | US | disclosed |
| US-9585824-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 2 in a medium comprising a fatty substance, processes and device | L'OREAL (FR) | 2017-03-07 | — | — | US | disclosed |
| US-20150374601-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2015-12-31 | — | — | US | disclosed |
| US-20150374601-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2015-12-31 | — | — | US | disclosed |
| WO-2014118234-A2 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |
| EP-0370880-B1 | TRIALKOXY-SUBSTITUTED M-PHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS COUPLING AGENTS IN THE OXIDATION DYEING OF KERATINIC FIBRES, ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1992-11-11 | — | — | EP | disclosed |
| EP-0370880-A1 | Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair | L'OREAL (FR) | 1990-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374601-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | KRT18, FABP4, FABP2 | KDM4E 2364/4885POLB 984/4885MAPT 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.