⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270208 | 1.00 | — | — | |
| SCHEMBL938761 | 0.94 | — | — | |
| SCHEMBL8470170 | 0.78 | — | — | |
| SCHEMBL514376 | 0.72 | — | — | |
| SCHEMBL434958 | 0.72 | — | — | |
| SCHEMBL269447 | 0.72 | — | — | |
| SCHEMBL6799285 | 0.72 | ALDH1A1 (0.46) | — | |
| SCHEMBL10871026 | 0.72 | ALDH1A1 (0.46) | — | |
| SCHEMBL437564 | 0.72 | — | — | |
| SCHEMBL228689 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | disclosed |
| EP-0125576-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-19 | — | — | EP | disclosed |
| US-4692516-A | Process for the manufacture of 3-pyridinium-methyl-cephalosporins | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0137442-A2 | Cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |
| EP-0137440-A2 | Cephalasporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |
| EP-0125576-A2 | Process for the preparation of cephalosporins | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |
| EP-0124889-A2 | Process for the preparation of cephalosporins | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-14 | — | — | EP | disclosed |
| EP-0111935-A2 | Cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-27 | — | — | EP | disclosed |