Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695189 | 0.94 | AGTR1 (0.61) | AGTR1 | |
| SCHEMBL9693707 | 0.94 | AGTR1 (0.61) | AGTR1 | |
| SCHEMBL9309457 | 0.93 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL9695715 | 0.93 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL9309941 | 0.89 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9694906 | 0.89 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL9310766 | 0.89 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL9694858 | 0.88 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9694851 | 0.88 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9309863 | 0.87 | AGTR1 (0.65) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | claimed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | claimed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |