Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694827 | 0.94 | AGTR1 (0.37) | PPARGAGTR1AGTR2KCNH2 | |
| SCHEMBL9695697 | 0.92 | PPARG (0.34) | PPARG | |
| SCHEMBL9310894 | 0.90 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9694718 | 0.90 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL9694927 | 0.89 | AGTR1 (0.37) | PPARGAGTR1AGTR2 | |
| SCHEMBL9309367 | 0.88 | AGTR1 (0.40) | PPARGAGTR1AGTR2 | |
| SCHEMBL9309706 | 0.88 | AGTR1 (0.40) | PPARGAGTR1AGTR2 | |
| SCHEMBL9694921 | 0.87 | HPGD (0.31) | — | |
| SCHEMBL9694828 | 0.86 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9310306 | 0.86 | AGTR1 (0.48) | PPARGAGTR1AGTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |