SCHEMBL969377

SCHEMBL969377

C=CC(=O)OC(C)C(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.43
HPGD P15428 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665734 0.81 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9352413 0.80 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Potassium Ion SCHEMBL31756936 0.80 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2184214 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27794908 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL37396 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10024379 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16520914 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL6368708 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL183980 0.77 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279731-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-22 US disclosed
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
CN-107406723-B Addition-fragmentation oligomers 3M创新有限公司 2021-05-07 CN disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
EP-3259323-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-02-26 EP disclosed
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-01-30 US disclosed
US-10479848-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-19 US disclosed
US-10471398-B2 Graft copolymer functionalized article 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-12 US disclosed
US-10370322-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-06 US disclosed
US-20020132927-A1 Pressure sensitive adhesives possessing high load bearing capability 3M INNOVATIVE PROPERTIES COMPANY 2002-09-19 US disclosed
US-6448337-B1 CURABLE SYRUP COMPRISING DUAL POLYMERS CONTAINING PENDANT INTERREACTIVE GROUPS, FREE RADICAL POLYMERIZABLE SOLVENT MONOMER AND PHOTOINITIATOR; BALANCED ADHESIVE AND COHESIVE CHARACTERISTICS 3M INNOVATIVE PROPERTIES COMPANY 2002-09-10 US disclosed
EP-1230315-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M Innovative Properties Company (US) 2002-08-14 EP disclosed
WO-2002038694-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-05-16 WO disclosed
EP-0808348-B1 CROSS-LINKABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING & MFG (US) 1999-05-06 EP disclosed
US-5741543-A CONTAINING UNSATURATED MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-21 US disclosed
EP-0808348-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-26 EP disclosed
WO-1996024644-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO disclosed
US-4378411-A HAVING ETHLENICALLY UNSATURATED PEPTIDE GROUPS; FOR GRAPHIC ARTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-03-29 US disclosed
US-4304705-A Radiation-curable polymers containing pendant unsaturated peptide groups derived from azlactone polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479848-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TSHR 4794/4885HPGD 3653/4885ALDH1A1 2212/4885
US-10370322-B2 Addition-fragmentation agents NR4A1, PARP14, MTX1 TSHR 1778/4885HPGD 3857/4885ALDH1A1 3630/4885
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS TSHR 4794/4885HPGD 3653/4885ALDH1A1 2212/4885
US-11279731-B2 Ligand functional substrates PCNA, POLM, POLL TSHR 4365/4885HPGD 3788/4885ALDH1A1 4565/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TSHR 4794/4885HPGD 3653/4885ALDH1A1 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.