Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693796 | 1.00 | MAPT (0.59) | MAPTALDH1A1KDM4EGAAPKM | |
| SCHEMBL9693493 | 0.90 | MAPT (0.51) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9693489 | 0.90 | MAPT (0.51) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9693731 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9693737 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9691948 | 0.89 | HPGD (0.51) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9691943 | 0.89 | HPGD (0.51) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9691833 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1846455 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1846457 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |