Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NCF1 | P14598 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13737643 | 0.87 | MAPT (0.53) | KDM4EALDH1A1TSHRCYP1A2HSD17B10 | |
| SCHEMBL19066027 | 0.83 | CYP1A2 (0.50) | KDM4EALDH1A1CYP1A2HSD17B10NCF1 | |
| SCHEMBL17186094 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1TSHRCYP1A2HSD17B10 | |
| SCHEMBL19066016 | 0.81 | MAPT (0.58) | KDM4EALDH1A1CYP1A2HSD17B10NCF1 | |
| SCHEMBL2323241 | 0.81 | KMT2A (0.54) | KDM4EALDH1A1TSHRHSD17B10NCF1 | |
| SCHEMBL10805765 | 0.80 | CYP1A2 (0.47) | KDM4EALDH1A1TSHRCYP1A2HSD17B10 | |
| SCHEMBL9694368 | 0.80 | MAOB (0.50) | KDM4EALDH1A1TSHRCYP1A2NCF1 | |
| SCHEMBL10366043 | 0.80 | CA12 (0.48) | KDM4EALDH1A1CYP1A2SMN1; SMN2HPGD | |
| SCHEMBL29629327 | 0.80 | NQO1 (0.68) | KDM4EALDH1A1TSHRCYP1A2HSD17B10 | |
| SCHEMBL3825385 | 0.80 | NQO1 (0.68) | KDM4EALDH1A1TSHRCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234067-A | 2, 5-disubstituted thiophene compounds and synthetic method thereof | 湘潭大学 | 2021-08-10 | — | — | CN | claimed |
| CN-109776406-B | Method for cross coupling of ether compound and quinoline derivative | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-119707786-A | Synthesis method of terminal alkyne | 南京工业大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-111440181-B | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-113264876-B | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-110776510-B | Preparation method of 1- (2-quinolyl) -beta-carboline natural product and derivative | 烟台大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113234067-B | 2, 5-disubstituted thiophene compounds and synthetic method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-113264876-A | Method for selectively catalyzing and hydrogenating aromatic heterocyclic compounds by non-hydrogen participation | 延安大学 | 2021-08-17 | — | — | CN | disclosed |
| CN-113234067-A | 2, 5-disubstituted thiophene compounds and synthetic method thereof | 湘潭大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-111440181-A | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-110790763-A | Process for preparing pyridobipyrimidine and pyridobipyrazole derivatives | 烟台大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110776510-A | Preparation method of 1- (2-quinolyl) - β -carboline natural product and derivative | 烟台大学 | 2020-02-11 | — | — | CN | disclosed |
| US-9481675-B2 | Gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-11-01 | — | — | US | disclosed |
| EP-0276842-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5035993-A | Quaternary ammonium salt nucleating agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4877723-A | EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4859579-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4828973-A | DIRECT POSITIVES WITH REVERSAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0276842-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |