SCHEMBL9694239

SCHEMBL9694239

Cc1nc2cc(Cl)c(Cl)cc2n1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
MAPK1 P28482 1/20 0.62
HTT P42858 1/20 0.62
HSD17B10 Q99714 1/20 0.56
KDM4E B2RXH2 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
DCTPP1 Q9H773 3/20 0.52
NPC1 O15118 2/20 0.51
CCNT1 O60563 1/20 0.49
CDK9 P50750 1/20 0.49
HCAR1 Q9BXC0 1/20 0.48
PTPN1 P18031 1/20 0.46
CYP1A2 P05177 1/20 0.45
PDE10A Q9Y233 1/20 0.45
MEN1 O00255 1/20 0.45
GLA P06280 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13916684 0.88 HTT (0.72) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL13916683 0.86 HTT (0.70) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL22219421 0.83 HTT (0.66) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL10980907 0.82 MAPK1 (0.65) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL541394 0.82 ALDH1A1 (0.68) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL614951 0.79 ALDH1A1 (1.00) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL1104826 0.79 HTT (0.60) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL1104823 0.78 ALDH1A1 (0.71) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL1104809 0.78 HTT (0.69) ALDH1A1MAPK1HTTHSD17B10KDM4E
SCHEMBL1440626 0.78 ALDH1A1 (0.47) ALDH1A1MAPK1HTTHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276842-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-07-29 EP disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4859579-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed
US-4828973-A DIRECT POSITIVES WITH REVERSAL PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-09 US disclosed
EP-0276842-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-08-03 EP disclosed