Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 3/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381645 | 0.82 | RAB9A (0.75) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL15087624 | 0.82 | RAB9A (0.75) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL5740526 | 0.81 | CRBN (0.69) | GRM5DDB1CRBN | |
| SCHEMBL4999518 | 0.81 | RAB9A (0.56) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL14856587 | 0.80 | RAB9A (0.61) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL14856267 | 0.79 | RAB9A (0.59) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL14856372 | 0.79 | RAB9A (0.59) | RAB9ANPC1KDM1AALDH1A1KDM4E | |
| SCHEMBL8312018 | 0.79 | GRM5 (0.59) | RAB9ANPC1KDM4EGRM5CHEK1 | |
| SCHEMBL26407280 | 0.78 | RAB9A (0.69) | RAB9ANPC1KDM1AKDM4EGRM5 | |
| SCHEMBL4077366 | 0.78 | RAB9A (0.68) | RAB9ANPC1KDM1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118806-A | Enzyme inhibitor for lipoxygenase; useful for treating cancer, hepatic diseases, inflammation, cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-02 | — | — | US | disclosed |