Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384688 | 0.81 | CTSA (0.41) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1532464 | 0.78 | KDM4E (0.64) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL7877115 | 0.77 | CYP1A2 (0.55) | ALDH1A1MAPTLMNAKMT2ANPSR1 | |
| SCHEMBL30615664 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL9384512 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL9384516 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL8713665 | 0.76 | NPSR1 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8713667 | 0.76 | NPSR1 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9767524 | 0.74 | ALDH1A1 (0.48) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9767528 | 0.74 | ALDH1A1 (0.48) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167693-A | Pre- and postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-01 | — | — | US | disclosed |
| EP-0459243-A2 | Substituted Azines | BAYER AG (DE) | 1991-12-04 | — | — | EP | disclosed |