Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.33 |
| ▸ | EDNRA | P25101 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694718 | 0.94 | AGTR1 (0.34) | AGTR1AGTR2EDNRA | |
| SCHEMBL9693538 | 0.93 | AGTR1 (0.34) | AGTR1AGTR2EDNRA | |
| SCHEMBL9694827 | 0.91 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9694855 | 0.90 | AGTR1 (0.35) | AGTR1AGTR2EDNRA | |
| SCHEMBL9310369 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2EDNRA | |
| SCHEMBL9694921 | 0.89 | HPGD (0.31) | MAPTALDH1A1GAA | |
| SCHEMBL9309814 | 0.89 | AGTR1 (0.35) | AGTR1AGTR2EDNRA | |
| SCHEMBL9309579 | 0.88 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9694927 | 0.87 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9309262 | 0.87 | AGTR1 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | claimed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | claimed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |