Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695283 | 0.93 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9695206 | 0.93 | AGTR1 (0.36) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL9693720 | 0.93 | AGTR1 (0.36) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL9309876 | 0.91 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9693664 | 0.91 | AGTR1 (0.36) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL9694971 | 0.91 | AGTR1 (0.36) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL9695156 | 0.89 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9694942 | 0.88 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9695231 | 0.88 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9693557 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |