Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694935 | 0.87 | PKM (0.54) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL9348700 | 0.83 | PKM (0.65) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL11197453 | 0.79 | PKM (0.56) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL23014465 | 0.77 | HTT (0.52) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL6644803 | 0.76 | SMN1; SMN2 (0.47) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL8036573 | 0.76 | MAPT (0.48) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL2905398 | 0.75 | PKM (0.59) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL9352517 | 0.75 | PKM (0.55) | PKMHTTTDP1KDM4EPOLB | |
| SCHEMBL27057188 | 0.75 | PKM (0.51) | PKMHTTTDP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL10426497 | 0.74 | MAPT (0.46) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370880-B1 | TRIALKOXY-SUBSTITUTED M-PHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS COUPLING AGENTS IN THE OXIDATION DYEING OF KERATINIC FIBRES, ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1992-11-11 | — | — | EP | disclosed |
| US-5002585-A | HAIR DYES, USED WITH PHENYLENEDIAMINES, AMINOPHENOLS AND AMINOPYRIDINES | L'OREAL (FR) | 1991-03-26 | — | — | US | disclosed |
| EP-0370880-A1 | Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair | L'OREAL (FR) | 1990-05-30 | — | — | EP | disclosed |