Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694594 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL27183087 | 0.86 | MAPT (0.67) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL10968481 | 0.83 | KMT2A (0.62) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL28007431 | 0.81 | MAPT (0.76) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3164409 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL9193599 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL20984965 | 0.77 | GAA (0.63) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL11075336 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL7573415 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL28030547 | 0.75 | ALDH1A1 (0.66) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | claimed |