Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PGR | P06401 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.40 |
| ▸ | STK10 | O94804 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695091 | 0.86 | ALDH1A1 (0.52) | ALDH1A1PGRMAOBHPGDKDM4E | |
| SCHEMBL5617626 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL9695122 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL5617562 | 0.80 | ALDH1A1 (0.48) | ALDH1A1PGRMAOBHPGDKDM4E | |
| SCHEMBL5618611 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL5618378 | 0.78 | ERN1 (0.47) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL5617520 | 0.77 | MAPT (0.55) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL9589052 | 0.77 | KDM4E (0.56) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL9695076 | 0.76 | BRD4 (0.53) | ALDH1A1MAOBHPGDKDM4EMEN1 | |
| SCHEMBL9695046 | 0.76 | MAPT (0.53) | ALDH1A1MAOBHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100914-A | Monoamine Oxidase Inhibitors, Central Nervous System Disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |