Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | ECE1 | P42892 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629526 | 0.95 | ECE1 (0.59) | ALDH1A1ALOX15NAALAD2ITGB3ITGA2B | |
| SCHEMBL11629522 | 0.95 | ECE1 (0.59) | ALDH1A1ALOX15NAALAD2ITGB3ITGA2B | |
| SCHEMBL19925534 | 0.91 | FOLH1 (0.64) | NAALAD2MMEECE1 | |
| SCHEMBL19307785 | 0.91 | FOLH1 (0.64) | NAALAD2MMEECE1 | |
| SCHEMBL9698236 | 0.91 | FOLH1 (0.64) | NAALAD2MMEECE1 | |
| SCHEMBL24238520 | 0.91 | FOLH1 (0.64) | NAALAD2MMEECE1 | |
| SCHEMBL9697060 | 0.91 | FOLH1 (0.64) | NAALAD2MMEECE1 | |
| SCHEMBL219151 | 0.89 | TACR1 (0.68) | ALDH1A1ALOX15ITGB3ITGA2BTACR1 | |
| SCHEMBL220648 | 0.89 | TACR1 (0.68) | ALDH1A1ALOX15ITGB3ITGA2BTACR1 | |
| SCHEMBL7372270 | 0.89 | TACR1 (0.68) | ALDH1A1ALOX15ITGB3ITGA2BTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |