SCHEMBL219151

SCHEMBL219151

O=C(N[C@H](Cc1ccccc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.68
ITGB3 P05106 6/20 0.67
ITGA2B P08514 6/20 0.67
CTSL P07711 2/20 0.67
CTSB P07858 2/20 0.67
CTSS P25774 2/20 0.67
CTSK P43235 2/20 0.67
ALDH1A1 P00352 1/20 0.65
ALOX15 P16050 1/20 0.65
CTRB1 P17538 2/20 0.64
MME P08473 1/20 0.62
ECE1 P42892 1/20 0.62
TYR P14679 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372270 1.00 TACR1 (0.68) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL220648 1.00 TACR1 (0.68) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL26661077 1.00 TACR1 (0.68) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL479010 1.00 TACR1 (0.68) TACR1ITGB3ITGA2BCTSLCTSB
Hypochlorous Acid SCHEMBL7368156 0.97 TACR1 (0.65) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL5391083 0.94 ITGB3 (0.65) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL12052836 0.94 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL1702159 0.94 ECE1 (0.65) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL221300 0.94 ECE1 (0.65) TACR1ITGB3ITGA2BCTSLCTSB
SCHEMBL10507966 0.94 ECE1 (0.65) TACR1ITGB3ITGA2BCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
US-20140135509-A1 Process for the Preparation of Benzyl [(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol]-4-yl]carbamate and Intermediates in the Process ASTRAZENECA AB (SE) 2014-05-15 US claimed
EP-2707363-A1 A PROCESS FOR THE PREPARATION OF BENZYL [(3AS,4R,6S,6AR)-6-HYDROXY-2,2- DIMETHYLTETRAHYDRO-3AH-CYCLOPENTA[D][1,3]DIOXOL]-4-YL]CARBAMATE AND INTERMEDIATES IN THE PROCESS AstraZeneca AB (SE) 2014-03-19 EP claimed
CN-103534245-A A process for the preparation of benzyl [(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol]-4-yl]carbamate and intermediates in the process ASTRAZENECA AB 2014-01-22 CN claimed
WO-2012158099-A1 A PROCESS FOR THE PREPARATION OF BENZYL [(3AS,4R,6S,6AR)-6-HYDROXY-2,2- DIMETHYLTETRAHYDRO-3AH-CYCLOPENTA[D][1,3]DIOXOL]-4-YL]CARBAMATE AND INTERMEDIATES IN THE PROCESS ASTRAZENECA AB (SE) 2012-11-22 WO claimed
CN-100429223-C Process for producing cyclo (D-phenylpropyl-D-group) dipeptide NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-10-29 CN claimed
CN-1557834-A Process for producing cyclo (D-phenylpropyl-D-group) dipeptide �Ͼ���ҵ��ѧ 2004-12-29 CN claimed
EP-0024182-B1 THERMO-STABLE MICRO-ORGANISM AND PROTEOLYTIC ENZYME PREPARED THEREFROM, AND PROCESSES FOR THE PREPARATION OF THE MICRO-ORGANISM AND THE PROTEOLYTIC ENZYME DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1986-05-07 EP claimed
US-4480036-A Proteolytic enzyme DEVELOPMENT FINANCE CORPORATION (NZ) 1984-10-30 US claimed
EP-0024182-A2 Thermo-stable micro-organism and proteolytic enzyme prepared therefrom, and processes for the preparation of the micro-organism and the proteolytic enzyme DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1981-02-25 EP claimed
JP-57193437-A None JP disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
WO-2025095479-A1 NOVEL PROSTATE SPECIFIC MEMBRANE ANTIGEN LIGAND AND USE THEREOF 서울대학교병원 2025-05-08 WO disclosed
EP-0024182-A2 Thermo-stable micro-organism and proteolytic enzyme prepared therefrom, and processes for the preparation of the micro-organism and the proteolytic enzyme DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1981-02-25 EP disclosed
US-4124703-A Luliberin analogs IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-11-07 US disclosed
US-4100274-A LULIBERIN ANTAGONIST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-07-11 US disclosed
US-4064270-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP TACR1 4246/4885ITGB3 1965/4885ITGA2B 3131/4885
US-20140135509-A1 Process for the Preparation of Benzyl [(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol]-4-yl]carbamate and Intermediates in the Process CYP4X1, CYP4B1, CBR3 TACR1 666/4885ITGB3 3065/4885ITGA2B 3841/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 TACR1 3107/4885ITGB3 2779/4885ITGA2B 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.